--Original published at Nadia's Blog
I chose the TED talk on how the brain may fix itself with help. I decided to chose this topic because I immediately was drawn to the scientific aspect of how the brain is able to work. Jocelyne Bloch began to explain how when there is damage to the human brain it most likely leads to an individual being handicap. Her as well as other doctors, have been trying to find evidence to repair the brain in a successful way. During a head trauma the brain begins to swell with pressure. The only way to decrease it is by removing a section of the brain tissue. When it was removed, they decided to study the tissue and attempt to grow new cells from that tissue, which they realized would be very difficult. Many attempts later they were able to grow new cells and soon realized they had created a new cell population that would divide slower and were able to die quicker. They created an experiment to discover if they could use these cells to help with brain repair. They first did a biopsy of the brain, then looked at the cell culture, labeled the cells they injected with colors in order to track them, and then re-implanted them in the same individual. They began testing this on monkeys, their control group was a normal monkey and they came to find that when injecting the cells into a normal monkey the cells were not needed and disappeared. They then injected the cells in the monkeys who had a lesion, and found that these cells remained, and began to mature into new neurons. Their experiment resulted in success and are now in the process of meeting the regulations for them to apply this concept on humans.
I found it interesting that they were able to track the exact cells that they had implanted into the brain by coloring them. To me this was surprising, since they are able to differentiate between millions and millions of cells. I felt that the presenter was very reliable because not only is this research in her field, but she is a very well educated neurosurgeon. I also felt that Bloch was reliable because along with her efforts in her study, they were also able to make progress and get logical and accurate results from their experiments.
Another research idea could be studying other types of brain tissues and applying the same process of studying the culture, labeling the cells and re-implanting them into the same individual, to see the affects of different cell tissues in the brain.