--Original published at Em
Background to major depressive disorder is Catatonia, delusions, destruction, disorder. Cognitive therapy which was established by cognitive behavioral therapy Beck et al. Antidepressants most commonly prescribe are ADMs.
Supports my perspective
I believe that the best treatment is a combination of antidepressants and cognitive therapy. While the patient is learning to cope mechanisms, and learning reframing techniques they still have the antidepressants to fall back on. There is a large amount of data that antidepressants treat moderate to severe depression. There is less data on cognitive therapy. The objective is to compare the efficacy is moderate to severe depression of antidepressant medications with cognitive therapy in a placebo controlled trial. The design is 16 weeks of cognitive therapy, 16 weeks of medication, and 8 weeks of pill placebo. The Hamilton Depression Rating Scale provided continuous severity scores. At week 8 50% of the medication and 43% groups were superior to placebo. At the end of the study cognitive therapy was just as effective as medications. Some limitations are the quality of the therapists. The Treatment of Depression Collaborative Research Program Compared cognitive therapy and Antidepressants and no differenced were observed between cognitive therapy and antidepressant patients.
The National institute of mental health first recommends antidepressants as treatment for major depressive disorder. Antidepressants alter the way the patient’s brain uses chemicals, so it is more efficient. The national institute of health leans towards these methods because they have empirical evidence of neurotransmitters. The National institute for metal health also discusses cognitive therapy but as a second option to antidepressants.
The in the national revision of neuroscience 2008 by the National institute of health. Patients are advised to take ADM for at least six months to prevent relapse. In the patient does not experience symptoms then they are said to be cured if they do have symptoms then they are prescribed antidepressants indeterminately. These patients are deemed to have chronic depression. The efficiency of ADMs has been established in “thousands of placebos controlled clinical trials.” ADMs seem to be symptom suppressive instead of curative. Lots of studies have shown that ADMs change the regulatory processes of the monoamine systems. Some negative effects are changes in sleeping, appetite sexual interest, and emotional response.
For cognitive therapy
In the United Kingdom’s National Health Service it is stated that cognitive therapy is as effective as antidepressants and therefore recommends cognitive therapy first. The antidepressants simply suppressed the side effects while the cognitive therapy got to the root of the problem and cure the problem. This study was carried out by the University of North Carolina International and Danube University. Then peer reviewed by the British medical journal. Some limitations are this is only for moderate depression some doctors think that severe depression need to be treated with antidepressants first.
The Time magazine used a PET scan to see the brain function when researchers took scans. The participants who got well had increased insula this is a region that assesses or signals pain. The pattern of insula levels predicted who would respond better to talk therapy or antidepressants. Those who responded best to talk therapy tended to have reduced insula compared to before. Cognitive therapy teaches the patients what their thoughts mean and teaches them coping techniques therefore is advised.
@maiasz, M. S. (2013, June 17). Talk Therapy or Antidepressant? A Brain Scan Predicts Which Works Best for Your Depression. Retrieved December 07, 2017, from http://healthland.time.com/2013/06/17/talk-therapy-or-antidepressant-a-brain-scan-predicts-which-works-best-for-your-depression/
Depression. (n.d.). Retrieved December 07, 2017, from https://www.nimh.nih.gov/health/topics/depression/index.shtml
DeRubeis, R. J., Siegle, G. J., & Hollon, S. D. (2008, October). Cognitive therapy vs. medications for depression: Treatment outcomes and neural mechanisms. Retrieved December 07, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748674/
Http://ljournal.ru/wp-content/uploads/2017/03/a-2017-023.pdf. (2017). doi:10.18411/a-2017-023
Talking therapy ‘as effective as antidepressants’ study finds. (n.d.). Retrieved December 07, 2017, from https://www.nhs.uk/news/mental-health/talking-therapy-as-effective-as-antidepressants-study-finds/