--Original published at Site Title
I chose to watch the TED talk about the brain’s ability to repair itself. The speaker was Siddharthan Chandran, a neurologist. I was drawn to watch this speech because of the reputation brain damage has. It seems like a diagnosis of a disease like Alzheimer’s is basically a sentence to a slow, painful death with no way of curing it. The title of the talk seemed to suggest that there could be a cure so I wanted to watch it and see what the speaker had to say.
Dr. Chandran started off by briefly describing how brain cells work and what can happen if they are damaged. He then showed them examples of damage through brain scans and and interview with a man named John who had Motor Neuron Disease. After apologizing for the doom and gloom he got to the hopeful part of his speech. Dr. Chandran told the audience, “The brain is able to repair itself, it just doesn’t do it well enough”. He showed the audience a brain scan that exemplified what he was talking about and then explained how the brain could be provoked to repair faster with the use of stem cells. That claim was backed up with by a study Dr. Chandran did along with a few other neurologists where stem cells were taken from bone marrow of Multiple Sclerosis patients, grown and place back in the vein. They then measured the optic nerve and saw that the stem cells were protecting the nerve. He finished off with another interview with John.
I found the clinical trial Dr. Chandran did with his colleagues to be the most interesting part of the talk. Even though it was on a small scale, it was good to see that what he was claiming was actually possible. Obviously there is still a long way to go but that is definitely a good place to start.
Dr. Chandran is a trustworthy source. He’s a neurologist so he has been through medical school and studies the brain for a living. Clearly that gives him the background to make the claims he is making. On top of having the right background, he even has a study to back it up. He didn’t just come with some theory that has yet to be tested; there is hard evidence that this could work. Because of that, I don’t have any doubt in Dr. Chandran.
The talk inspired a research idea of my own. It would most likely have to take place further down the road, once more studies are done on the ability of stem cells to repair brain damage. Once neurologists are at a point where they believe they could safely and effectively use stem cells to repair brain damage, they could give patients the option of receiving experimental treatment to cure brain diseases like multiple sclerosis. They could track the damage to a patient’s brain over a certain period of time, say a year, give them the “cure” and track what it does. This can be done by brain scans just like the ones Dr. Chandran used. If the damage is being repaired, then the cure is working. There isn’t much bias in this experiment. I would believe that most brains would react the same way to the stem cells being introduced. On top of that, the experiment is ethical. You can give the patient the option to try the treatment or not.